Consiration of text weight translates directly to design weight all across. Text is meant to be read, therefore even weight helps the eye move quickly, smoothly across it like a well-paved road. This might not be the goal you're shooting for in a page design though!

Aliasing and antialiasing is a big deal with web design as well. Oftentimes making your designs match the pixel grid will render them uniquely sharp allowing smaller details to be visible. If you miss the pixel grid you'll deal with antialiasing tech which will induce a subtle blur. Either effect may be desirable.

Finally, it's always worth refreshing the value of detail in design. The pixel level comparison of Garamond, Helvetica, and Comic Sans can be inspiration for the level of detail required to make a truly lively design.

Thanks, that sounds so well thought out and reinforces to me that there's a lot I need to learn.

But at the same time, I barely understand what you wrote :(

A lot of people forget text is also interaction and communication. The soft forms of Comic Sans communicate a soft voice, a party feeling, an informal tone. Font's like Helvetica are formal, almost cold, just to inform you without any emotion. So using a font like Helvetica is more suitable for business. But it's bullshit to hate Comic Sans. It's just a different font.