I would have assumed that connecting your PC to a hub built-in to your monitor then connecting keyboard and mice into the monitor would be a somewhat common configuration
I don't know; I tried this once (on a Dell U2715H), and the input from both the mouse and the keyboard got very jittery, to the point of making the computer very difficult to operate. I suppose there was some interference from processing and displaying HDMI signal; whatever it was, I decided not to bother with built-in display USB hubs.
