Liposomal C IS NOT ascorbyl palmitate. The point is about liposome anyway, not the form of vitamin C. There are a number of research papers showing higher bioavailability, some even claim its similar to IV.
Ah, so you are actually talking about the liposome encased ascorbic acid. I have seen a number of products that misrepresented ascorbyl palmitate as liposomal vitamin C, hence the enquiry.
Taking any form of vitamin C orally still confers statistically insignificant benefits for the skin due to having to propagate and get distributed throughout the entire body.
The article in question discusses the benefits of the topical application of vitamin C, the benefits of which have been extensively studied. Vitamin C (especially in combination with ferulic acid) is amongst very few skincare products that actually work – it has been known for a long time.
> Taking any form of vitamin C orally still confers statistically insignificant benefits for the skin due to having to propagate and get distributed throughout the entire body.
Maybe not if you take it in multiple of grams, e.g. you brute force it to replace non-working GULO gene you have, that would do it in that range if not defective.
> Taking vitamin C by grams will give one a diarrhoea, and a pretty violent one.
Yes when your body gets enough of it (its called Vitamin C Flush and its not harmful), which is dynamic. I take 10+ grams and do not have diarrhoea, I might get it on 20+ IF I am healthy. I don't get it with 100g when I have influenza which is the state of the system when body requires more and SVCT pumps are active like crazy. This is trivially easy to check out yourself, you don't need a study. I have never seen a better feedback system for any drug, really.
> Can you explain and cite a study reference?
There are no studies about it, you need to try it yourself. Vitamin C is non-toxic and doesn't produce kidney stones, contrary to popular belief.
There are medical hypothesis and Linus Pauling wrote a few books about it long time ago.
> One of the common strategies to prolong the circulation of vitamin C is to recycle it by coupling it with, e.g. N-acetyl cysteine.
Yes, I take NAC too, however, the worst offender is sugar, as GLUT2 transports both C and glucose, and since its passive transporter C gets outcompeted given the levels of both.
I can explain 2 decades of experience with it, if you need some info send me a note.
